Basic Information
ID: ALA3614715
Type: Binding
Description: Inhibition of FTO (unknown origin) (31 to 505 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in 3-meT substrate demethylation by measuring demethylation ratio at 80 uM incubated for 17 hrs at 16 degC by HPLC method
Organism: Homo sapiens
Cell type: BL21-DE3
Activity Charts
Bioactivity
Activity Types for Assay ALA3614715
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 317.77 | 3.81 | 3.81 |
| 352.22 | 4.47 | 4.47 |
| 352.22 | 4.47 | 4.47 |
| 352.22 | 4.47 | 4.47 |
| 396.67 | 4.57 | 4.57 |
| 396.67 | 4.57 | 4.57 |
| 396.67 | 4.57 | 4.57 |
| 385.77 | 4.83 | 4.83 |
| 362.77 | 3.72 | 3.72 |
| 373.88 | 5.15 | 5.15 |
| 373.88 | 5.15 | 5.15 |
| 333.77 | 3.52 | 3.52 |
| 333.77 | 3.52 | 3.52 |
| 409.87 | 5.60 | 5.60 |
| 353.75 | 4.09 | 4.09 |
| 386.66 | 5.12 | 5.12 |
| 453.77 | 5.85 | 5.85 |
| 407.77 | 3.63 | 3.63 |
| 367.83 | 4.96 | 4.96 |
| 367.83 | 4.96 | 4.96 |