Basic Information
ID: ALA3615486
Type: Binding
Description: Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 mins
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3615486
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 387.51 | 2.65 | 2.65 |
| 464.59 | 3.72 | 3.72 |
| 499.04 | 4.37 | 4.37 |
| 443.61 | 3.95 | 3.95 |
| 455.50 | 3.67 | 3.67 |
| 455.50 | 3.67 | 3.67 |
| 491.56 | 3.22 | 3.22 |
| 419.45 | 4.12 | 4.12 |
| 372.37 | 3.21 | 3.21 |
| 469.53 | 4.06 | 4.06 |
| 455.50 | 3.67 | 3.67 |
| 483.56 | 4.45 | 4.45 |
| 469.53 | 4.06 | 4.06 |
| 481.54 | 4.21 | 4.21 |
| 513.55 | 5.31 | 5.31 |
| 473.49 | 3.81 | 3.81 |
| 523.50 | 4.69 | 4.69 |
| 500.50 | 3.58 | 3.58 |
| 470.52 | 3.25 | 3.25 |