Basic Information
ID: ALA3615570
Type: Binding
Description: Inhibition of calf thymus Top1-mediated pBR322 DNA relaxation at 25 uM preincubated for 15 mins measured after 30 mins by ethidium bromide staining relative to camptothecin
Organism: Bos taurus
Activity Charts
Bioactivity
Activity Types for Assay ALA3615570
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.08 | 2.08 |
| 320.30 | 2.29 | 2.29 |
| 347.37 | 2.59 | 2.59 |
| 359.39 | 2.74 | 2.74 |
| 361.36 | 1.58 | 1.58 |
| 374.40 | 1.50 | 1.50 |
| 362.39 | 1.40 | 1.40 |
| 395.42 | 3.08 | 3.08 |
| 404.43 | 1.17 | 1.17 |
| 417.47 | 1.09 | 1.09 |
| 388.43 | 1.94 | 1.94 |
| 385.38 | 1.74 | 1.74 |
| 376.42 | 1.79 | 1.79 |
| 404.47 | 2.57 | 2.57 |
| 409.45 | 3.47 | 3.47 |
| 416.48 | 2.72 | 2.72 |
| 418.45 | 1.56 | 1.56 |
| 431.50 | 1.48 | 1.48 |
| 402.45 | 2.33 | 2.33 |
| 397.39 | 2.90 | 2.90 |
| 403.44 | 2.75 | 2.75 |
| 405.41 | 1.60 | 1.60 |
| 417.47 | 3.14 | 3.14 |
| 419.44 | 1.99 | 1.99 |
| 403.44 | 2.75 | 2.75 |