Basic Information
ID: ALA3615799
Type: Binding
Description: Displacement of 5-({[2-({[3-({4-[(5-hydroxy-2-methylphenyl)amino]-2-pyrimidinyl}amino)phenyl]carbonyl}amino)-ethyl]amino}carbonyl)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid from His6-MBP-TEV-full length human TNNI3K expressed in Baculovirus expression system after 60 mins by fluorescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3615799
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 304.34 | 1.00 | 1.00 |
| 322.33 | 1.14 | 1.14 |
| 318.36 | 1.01 | 1.01 |
| 319.35 | 0.59 | 0.59 |
| 338.78 | 1.66 | 1.66 |
| 304.34 | 1.00 | 1.00 |
| 303.35 | 1.61 | 1.61 |
| 317.37 | 1.62 | 1.62 |
| 302.36 | 2.21 | 2.21 |
| 319.35 | 0.62 | 0.62 |
| 318.36 | 1.39 | 1.39 |
| 290.31 | 0.74 | 0.74 |
| 306.31 | 0.76 | 0.76 |
| 318.36 | 1.35 | 1.35 |
| 303.35 | 1.89 | 1.89 |
| 318.36 | 1.31 | 1.31 |
| 318.36 | 1.31 | 1.31 |
| 317.37 | 1.63 | 1.63 |
| 304.33 | 1.66 | 1.66 |
| 304.34 | 1.00 | 1.00 |
| 317.37 | 1.92 | 1.92 |
| 345.43 | 2.73 | 2.73 |
| 359.46 | 2.81 | 2.81 |
| 321.34 | 1.75 | 1.75 |
| 337.79 | 2.26 | 2.26 |
| 382.24 | 2.37 | 2.37 |
| 379.45 | 3.28 | 3.28 |
| 413.89 | 3.93 | 3.93 |
| 413.89 | 3.93 | 3.93 |
| 413.89 | 3.93 | 3.93 |
| 409.47 | 3.29 | 3.29 |
| 380.43 | 2.67 | 2.67 |
| 408.49 | 2.74 | 2.74 |
| 423.45 | 2.97 | 2.97 |
| 382.24 | 2.37 | 2.37 |
| 379.45 | 3.28 | 3.28 |
| 393.47 | 3.59 | 3.59 |
| 393.47 | 3.59 | 3.59 |
| 393.47 | 3.59 | 3.59 |
| 447.44 | 4.30 | 4.30 |
| 395.44 | 2.98 | 2.98 |
| 380.43 | 2.67 | 2.67 |
| 347.36 | 1.31 | 1.31 |
| 353.41 | 2.76 | 2.76 |
| 317.37 | 1.92 | 1.92 |
| 337.79 | 2.26 | 2.26 |
| 332.39 | 1.65 | 1.65 |
| 346.42 | 1.68 | 1.68 |
| 388.45 | 1.45 | 1.45 |
| 360.44 | 1.98 | 1.98 |
| 425.31 | 2.44 | 2.44 |
| 402.48 | 1.75 | 1.75 |
| 467.35 | 2.21 | 2.21 |
| 425.31 | 2.44 | 2.44 |
| 490.51 | 4.36 | 4.36 |
| 467.35 | 2.21 | 2.21 |
| 532.55 | 4.13 | 4.13 |