Basic Information
ID: ALA3616153
Type: Binding
Description: Inhibition of human DGAT1 expressed in human Hep3B cells incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and luminometry based flash plate assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Hep 3B2
Target: Diacylglycerol O-acyltransferase 1(ALA6009)
Document: ALA3611966
Inhibition of human DGAT1 expressed in human Hep3B cells incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and luminometry based flash plate assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3616153
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 458.56 | 3.60 | 3.60 |
| 358.44 | 2.03 | 2.03 |
| 477.56 | 3.90 | 3.90 |
| 498.60 | 3.05 | 3.05 |
| 462.55 | 3.50 | 3.50 |
| 512.61 | 4.66 | 4.66 |
| 538.64 | 5.17 | 5.17 |
| 597.59 | 5.18 | 5.18 |
| 596.61 | 4.71 | 4.71 |
| 526.63 | 5.05 | 5.05 |
| 552.67 | 5.56 | 5.56 |
| 526.63 | 5.05 | 5.05 |
| 552.67 | 5.56 | 5.56 |
| 512.61 | 4.66 | 4.66 |
| 512.61 | 4.66 | 4.66 |
| 538.64 | 5.17 | 5.17 |
| 538.64 | 5.17 | 5.17 |
| 552.67 | 5.48 | 5.48 |
| 606.64 | 6.19 | 6.19 |
| 573.09 | 5.83 | 5.83 |
| 573.09 | 5.83 | 5.83 |
| 566.70 | 5.79 | 5.79 |
| 607.53 | 6.48 | 6.48 |
| 574.62 | 5.45 | 5.45 |