Basic Information
ID: ALA3616305
Type: Functional
Description: Analgesic activity in mouse chronic constriction injury model of neuropathic pain assessed as protection of ipsilateral hind paw mechanoallodynia of sciatic nerve at 0.3 to 30 umol/kg administered through oral gavage at point of peak pain on day 7 measured at 3 hrs
Organism: Mus musculus
Tissue: Sciatic nerve
Activity Charts
Bioactivity
Activity Types for Assay ALA3616305
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 458.93 | 1.01 | 1.01 |
| 472.96 | 1.40 | 1.40 |
| 486.99 | 1.79 | 1.79 |
| 501.01 | 2.18 | 2.18 |
| 486.99 | 1.79 | 1.79 |
| 484.97 | 1.54 | 1.54 |
| 499.00 | 1.93 | 1.93 |
| 499.00 | 1.79 | 1.79 |
| 513.02 | 2.18 | 2.18 |
| 457.94 | 1.62 | 1.62 |
| 471.97 | 2.01 | 2.01 |