Assay Report Card

Basic Information

ID: ALA3618875

Type: Toxicity

Description: Selectivity index, ratio of toxicity against human Huh7ET cells assessed as reduction in beta-actin RNA levels at 20 uM to antiviral activity against HCV infected in human Huh7ET cells assessed as reduction in HCV RNA-derived luciferase activity at 20 uM by luciferase reporter gene assay

Cell type: Huh-7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
412.575.065.06
485.675.585.58
522.643.363.36
497.684.654.65
630.785.565.56
443.634.244.24
442.604.424.42