Basic Information
ID: ALA3618962
Type: Binding
Description: Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by fluorescent assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3618962
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 217.23 | 0.43 | 0.43 |
| 307.36 | 2.46 | 2.46 |
| 321.38 | 2.77 | 2.77 |
| 355.83 | 3.42 | 3.42 |
| 371.83 | 3.12 | 3.12 |
| 315.38 | 1.69 | 1.69 |
| 342.79 | 2.51 | 2.51 |
| 387.24 | 2.62 | 2.62 |
| 359.79 | 3.25 | 3.25 |
| 359.79 | 3.25 | 3.25 |
| 377.78 | 3.39 | 3.39 |
| 404.24 | 3.36 | 3.36 |
| 418.27 | 3.92 | 3.92 |
| 418.27 | 3.92 | 3.92 |
| 373.82 | 3.64 | 3.64 |
| 418.27 | 3.75 | 3.75 |
| 432.30 | 4.31 | 4.31 |
| 391.81 | 3.78 | 3.78 |
| 436.26 | 3.89 | 3.89 |
| 355.79 | 2.75 | 2.75 |
| 313.36 | 1.01 | 1.01 |
| 218.22 | 0.60 | 0.60 |
| 250.26 | 1.49 | 1.49 |
| 202.22 | 0.77 | 0.77 |
| 362.23 | 2.74 | 2.74 |
| 317.78 | 2.64 | 2.64 |
| 341.80 | 3.11 | 3.11 |
| 386.25 | 3.22 | 3.22 |
| 389.85 | 3.75 | 3.75 |
| 327.78 | 2.72 | 2.72 |
| 355.83 | 3.50 | 3.50 |
| 355.83 | 3.36 | 3.36 |
| 369.86 | 3.75 | 3.75 |
| 343.77 | 2.31 | 2.31 |
| 379.81 | 3.34 | 3.34 |
| 355.83 | 3.15 | 3.15 |
| 341.80 | 3.11 | 3.11 |
| 342.79 | 3.08 | 3.08 |
| 342.79 | 3.08 | 3.08 |
| 340.81 | 3.29 | 3.29 |
| 355.79 | 2.75 | 2.75 |