Basic Information
ID: ALA3619417
Type: Functional
Description: Antagonist activity at human recombinant mGlu3 receptor expressed in AV12 cells assessed as inhibition of glutamate-stimulated Ca2+ mobilization after 1.5 hrs by FLIPR assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: AV12
Target: Metabotropic glutamate receptor 3(ALA2888)
Document: ALA3616378
Antagonist activity at human recombinant mGlu3 receptor expressed in AV12 cells assessed as inhibition of glutamate-stimulated Ca2+ mobilization after 1.5 hrs by FLIPR assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3619417
Imax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 293.34 | 1.28 | 1.28 |
| 293.34 | 1.28 | 1.28 |
| 284.30 | -0.60 | -0.60 |
| 334.30 | 0.34 | 0.34 |
| 299.31 | -1.02 | -1.02 |
| 326.38 | 0.52 | 0.52 |
| 284.30 | -0.60 | -0.60 |
| 284.30 | -0.60 | -0.60 |
| 298.32 | -0.29 | -0.29 |
| 352.29 | 0.42 | 0.42 |
| 334.30 | 0.34 | 0.34 |
| 299.31 | -1.02 | -1.02 |
| 326.38 | 0.52 | 0.52 |
| 284.30 | -0.60 | -0.60 |