Basic Information
ID: ALA3619492
Type: Binding
Description: Inhibition of ERCC1-XPF in human A375 cells assessed as induction of delay in DNA repair by measuring cumulative frequency of cells up to 10 uM pre-incubated for 1 hr before cisplatin exposure for 1 hr by immunohistochemistry based gammaH2AX foci assay
Organism: Homo sapiens
Cell type: A-375
Activity Charts
Bioactivity
Activity Types for Assay ALA3619492
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 251.27 | 0.56 | 0.56 |