Basic Information
ID: ALA3619823
Type: Binding
Description: Inhibition of gamma-secretase in rat primary neuronal cells assessed as reduction in amyloid beta (1 to 42) production
Organism: Rattus norvegicus
Cell type: Primary neuron
Activity Charts
Bioactivity
Activity Types for Assay ALA3619823
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 415.28 | 5.34 | 5.34 |
| 455.35 | 6.15 | 6.15 |
| 455.35 | 6.15 | 6.15 |
| 455.35 | 6.15 | 6.15 |
| 469.37 | 6.54 | 6.54 |
| 441.32 | 5.76 | 5.76 |
| 453.33 | 6.06 | 6.06 |
| 457.32 | 5.34 | 5.34 |
| 420.90 | 5.50 | 5.50 |
| 454.45 | 5.86 | 5.86 |
| 404.45 | 4.98 | 4.98 |
| 416.48 | 4.85 | 4.85 |
| 471.56 | 4.68 | 4.68 |
| 454.45 | 5.86 | 5.86 |
| 454.45 | 5.86 | 5.86 |
| 488.90 | 6.52 | 6.52 |
| 522.45 | 6.88 | 6.88 |
| 488.90 | 6.52 | 6.52 |
| 488.90 | 6.52 | 6.52 |
| 488.90 | 6.52 | 6.52 |