Basic Information
ID: ALA3620444
Type: Binding
Description: Inhibition of ERCC1-XPF in human A375 cells assessed as induction of delay in DNA repair by measuring cumulative frequency of cells at 10 uM pre-incubated for 1 hr before 5 uM cisplatin exposure for 1 hr and measured after 6 hrs by immunohistochemistry based gammaH2AX foci assay (Rvb = 45.43%)
Organism: Homo sapiens
Cell type: A-375
Activity Charts
Bioactivity
Activity Types for Assay ALA3620444
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 326.18 | 3.26 | 3.26 |