Basic Information
ID: ALA3624059
Type: Binding
Description: Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate addition measured every 30 secs for 1 hr
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3624059
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 605.79 | 5.16 | 5.16 |
| 595.75 | 5.86 | 5.86 |
| 629.77 | 6.78 | 6.78 |
| 643.79 | 6.65 | 6.65 |
| 567.69 | 5.08 | 5.08 |
| 554.65 | 4.74 | 4.74 |
| 679.87 | 4.70 | 4.70 |
| 624.79 | 5.01 | 5.01 |
| 611.70 | 4.54 | 4.54 |
| 647.78 | 6.29 | 6.29 |
| 635.81 | 6.78 | 6.78 |
| 583.74 | 6.63 | 6.63 |
| 573.10 | 5.69 | 5.69 |
| 538.65 | 5.04 | 5.04 |
| 619.82 | 4.68 | 4.68 |
| 564.74 | 5.00 | 5.00 |
| 478.60 | 5.02 | 5.02 |
| 496.59 | 5.16 | 5.16 |
| 496.59 | 5.16 | 5.16 |
| 464.57 | 4.98 | 4.98 |
| 512.61 | 5.09 | 5.09 |
| 430.56 | 4.45 | 4.45 |
| 651.82 | 4.28 | 4.28 |
| 575.72 | 2.08 | 2.08 |
| 562.68 | 2.42 | 2.42 |
| 518.67 | 2.72 | 2.72 |
| 603.77 | 2.81 | 2.81 |
| 548.69 | 3.13 | 3.13 |
| 462.55 | 3.16 | 3.16 |
| 560.70 | 2.91 | 2.91 |
| 488.64 | 3.11 | 3.11 |
| 402.50 | 3.14 | 3.14 |
| 500.65 | 2.89 | 2.89 |