Basic Information
ID: ALA3624350
Type: Binding
Description: Inhibition of human CYP11B2 expressed in V79 cells assessed as aldosterone level after 3 hrs by HTRF assay in presence of 125 nM 11-deoxycorticosterone
Organism: Homo sapiens
Cell type: V79
Activity Charts
Bioactivity
Activity Types for Assay ALA3624350
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 334.42 | 3.62 | 3.62 |
| 312.38 | 3.89 | 3.89 |
| 248.29 | 2.43 | 2.43 |
| 262.32 | 2.74 | 2.74 |
| 288.35 | 3.31 | 3.31 |
| 316.29 | 3.45 | 3.45 |
| 330.44 | 4.48 | 4.48 |
| 324.39 | 4.09 | 4.09 |
| 280.31 | 2.88 | 2.88 |
| 330.31 | 3.76 | 3.76 |
| 320.35 | 2.52 | 2.52 |
| 319.37 | 2.10 | 2.10 |
| 333.40 | 2.44 | 2.44 |
| 340.41 | 2.14 | 2.14 |
| 402.48 | 3.57 | 3.57 |
| 320.40 | 2.96 | 2.96 |
| 362.43 | 3.19 | 3.19 |
| 374.37 | 3.67 | 3.67 |
| 374.37 | 3.51 | 3.51 |
| 374.37 | 3.51 | 3.51 |
| 428.34 | 4.22 | 4.22 |
| 428.34 | 4.22 | 4.22 |