Basic Information
ID: ALA3625051
Type: Binding
Description: Inhibition of squalene synthase in rat liver microsomes assessed as reduction in conversion of [3H]farnesyl pyrophosphate to squalene at 10 uM incubated for 30 mins by liquid scintillation counting method
Format: BAO_0000019
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Squalene synthetase(ALA3815)
Document: ALA3621067
Inhibition of squalene synthase in rat liver microsomes assessed as reduction in conversion of [3H]farnesyl pyrophosphate to squalene at 10 uM incubated for 30 mins by liquid scintillation counting method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3625051
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 356.30 | 2.84 | 2.84 |
| 396.37 | 3.76 | 3.76 |
| 410.40 | 4.15 | 4.15 |
| 395.25 | 2.37 | 2.37 |
| 435.32 | 3.29 | 3.29 |
| 449.35 | 3.68 | 3.68 |
| 406.32 | 3.09 | 3.09 |
| 420.35 | 3.48 | 3.48 |
| 406.36 | 3.76 | 3.76 |
| 446.43 | 4.68 | 4.68 |
| 460.46 | 5.07 | 5.07 |
| 374.28 | 3.10 | 3.10 |
| 414.34 | 4.02 | 4.02 |
| 428.37 | 4.41 | 4.41 |