Inhibition of squalene synthase in rat liver microsomes assessed as reduction in conversion of [3H]farnesyl pyrophosphate to squalene at 50 uM incubat...

Basic Information

ID: ALA3625052

Type: Binding

Description: Inhibition of squalene synthase in rat liver microsomes assessed as reduction in conversion of [3H]farnesyl pyrophosphate to squalene at 50 uM incubated for 30 mins by liquid scintillation counting

Format: BAO_0000019

Organism: Rattus norvegicus

Tissue: Liver

Subcellular Fraction: Microsomes

Target:  Squalene synthetase(ALA3815)

Document:  ALA3621067

Inhibition of squalene synthase in rat liver microsomes assessed as reduction in conversion of [3H]farnesyl pyrophosphate to squalene at 50 uM incubated for 30 mins by liquid scintillation counting: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
359.291.291.29
399.352.212.21
413.382.602.60