Basic Information
ID: ALA3625056
Type: Binding
Description: Inhibition of squalene synthase in rat liver microsomes assessed as reduction in conversion of [3H]farnesyl pyrophosphate to squalene incubated for 30 mins by liquid scintillation counting
Format: BAO_0000019
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Squalene synthetase(ALA3815)
Document: ALA3621067
Inhibition of squalene synthase in rat liver microsomes assessed as reduction in conversion of [3H]farnesyl pyrophosphate to squalene incubated for 30 mins by liquid scintillation counting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3625056
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 356.30 | 2.84 | 2.84 |
| 396.37 | 3.76 | 3.76 |
| 410.40 | 4.15 | 4.15 |
| 374.28 | 3.10 | 3.10 |
| 414.34 | 4.02 | 4.02 |
| 428.37 | 4.41 | 4.41 |