Antagonist activity at human orexin 1 receptor Ile408-Val mutant expressed in CHO cells assessed as inhibition of orexin-A-induced intracellular calci...

Basic Information

ID: ALA3625145

Type: Binding

Description: Antagonist activity at human orexin 1 receptor Ile408-Val mutant expressed in CHO cells assessed as inhibition of orexin-A-induced intracellular calcium level after 60 mins by FLIPR assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: CHO

Target: Unchecked(ALA612545)

Document: ALA3621132

Antagonist activity at human orexin 1 receptor Ile408-Val mutant expressed in CHO cells assessed as inhibition of orexin-A-induced intracellular calcium level after 60 mins by FLIPR assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3625145

IC50

Total(17)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
431.48	3.09	3.09
450.93	4.11	4.11
391.48	2.42	2.42
432.32	3.11	3.11
411.90	2.76	2.76
425.92	3.07	3.07
425.92	3.07	3.07
421.51	2.42	2.42
479.89	3.78	3.78
465.87	3.47	3.47
459.48	3.43	3.43
475.48	3.13	3.13
445.45	3.13	3.13
461.45	2.83	2.83
465.87	3.47	3.47
445.45	3.13	3.13
411.90	2.76	2.76