Basic Information
ID: ALA3625146
Type: Functional
Description: Antagonist activity at human orexin 2 receptor expressed in CHO cells assessed as inhibition of orexin-A-induced intracellular calcium level after 60 mins by FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Orexin receptor 2(ALA4792)
Document: ALA3621132
Antagonist activity at human orexin 2 receptor expressed in CHO cells assessed as inhibition of orexin-A-induced intracellular calcium level after 60 mins by FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3625146
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 431.48 | 3.09 | 3.09 |
| 450.93 | 4.11 | 4.11 |
| 391.48 | 2.42 | 2.42 |
| 432.32 | 3.11 | 3.11 |
| 411.90 | 2.76 | 2.76 |
| 425.92 | 3.07 | 3.07 |
| 425.92 | 3.07 | 3.07 |
| 421.51 | 2.42 | 2.42 |
| 479.89 | 3.78 | 3.78 |
| 465.87 | 3.47 | 3.47 |
| 459.48 | 3.43 | 3.43 |
| 475.48 | 3.13 | 3.13 |
| 445.45 | 3.13 | 3.13 |
| 461.45 | 2.83 | 2.83 |
| 465.87 | 3.47 | 3.47 |
| 445.45 | 3.13 | 3.13 |
| 411.90 | 2.76 | 2.76 |
| 461.45 | 2.83 | 2.83 |