Basic Information
ID: ALA3625149
Type: ADME
Description: Bioactivation of compound in rat liver microsomes assessed as AUC of GSH-adduct formation at 10 uM after 60 mins by HRMS analysis relative to labetalol
Format: BAO_0000019
Organism: Rattus norvegicus
Tissue: Liver
Target: Liver microsome(ALA2367428)
Document: ALA3621132
Bioactivation of compound in rat liver microsomes assessed as AUC of GSH-adduct formation at 10 uM after 60 mins by HRMS analysis relative to labetalol: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3625149
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 431.48 | 3.09 | 3.09 |
| 450.93 | 4.11 | 4.11 |
| 475.48 | 3.13 | 3.13 |