Basic Information
ID: ALA3626067
Type: Binding
Description: Inhibition of human SETD8 catalytic domain expressed in Escherichia coli assessed as reduction in transfer of tritiated methyl group from [3H]SAM to biotinylated H4 (1 to 24) peptide substrate by scintillation proximity assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3626067
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 522.72 | 3.70 | 3.70 |
| 489.66 | 5.50 | 5.50 |
| 399.54 | 3.62 | 3.62 |
| 457.62 | 3.94 | 3.94 |
| 471.65 | 4.33 | 4.33 |
| 457.62 | 3.68 | 3.68 |
| 470.62 | 3.04 | 3.04 |
| 457.58 | 1.02 | 1.02 |
| 441.62 | 4.71 | 4.71 |
| 401.56 | 3.78 | 3.78 |
| 373.50 | 3.18 | 3.18 |
| 399.54 | 3.44 | 3.44 |
| 399.54 | 3.57 | 3.57 |
| 371.49 | 2.93 | 2.93 |
| 385.51 | 3.18 | 3.18 |
| 428.54 | 1.87 | 1.87 |
| 428.54 | 1.87 | 1.87 |
| 443.55 | 0.68 | 0.68 |
| 435.52 | 3.78 | 3.78 |
| 427.59 | 4.17 | 4.17 |
| 470.66 | 3.86 | 3.86 |
| 484.69 | 4.25 | 4.25 |
| 498.72 | 4.64 | 4.64 |
| 512.74 | 5.03 | 5.03 |
| 449.60 | 5.09 | 5.09 |
| 479.63 | 5.10 | 5.10 |
| 494.60 | 5.00 | 5.00 |
| 435.57 | 5.07 | 5.07 |
| 465.60 | 5.08 | 5.08 |
| 503.57 | 6.09 | 6.09 |
| 480.57 | 4.98 | 4.98 |
| 420.56 | 4.99 | 4.99 |
| 450.58 | 5.00 | 5.00 |
| 488.55 | 6.01 | 6.01 |
| 453.56 | 5.21 | 5.21 |
| 353.51 | 3.91 | 3.91 |
| 383.54 | 3.92 | 3.92 |
| 383.54 | 3.92 | 3.92 |
| 427.59 | 4.32 | 4.32 |
| 441.62 | 4.70 | 4.70 |
| 417.99 | 4.57 | 4.57 |
| 427.59 | 4.32 | 4.32 |
| 441.62 | 4.70 | 4.70 |