Basic Information
ID: ALA3626114
Type: Binding
Description: Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldosterone after 16 hrs by HTRF assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Cytochrome P450 11B2(ALA2722)
Document: ALA3621059
Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldosterone after 16 hrs by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3626114
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 180.21 | 2.62 | 2.62 |
| 249.32 | 2.96 | 2.96 |
| 291.35 | 3.13 | 3.13 |
| 305.38 | 3.52 | 3.52 |
| 319.41 | 3.77 | 3.77 |
| 316.35 | 3.93 | 3.93 |
| 334.34 | 4.07 | 4.07 |
| 332.81 | 4.44 | 4.44 |
| 332.81 | 4.44 | 4.44 |
| 305.38 | 3.52 | 3.52 |
| 305.38 | 3.52 | 3.52 |