Basic Information
ID: ALA3626178
Type: ADME
Description: Inhibition of CYP3A4 in human liver microsomes at 10 uM pre-incubated for 10 mins before midazolam substrate and NADPH addition by LC-MS/MS method
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA3626178
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.41 | 4.52 | 4.52 |
| 396.45 | 3.96 | 3.96 |
| 413.51 | 4.64 | 4.64 |
| 395.47 | 4.48 | 4.48 |
| 411.47 | 4.32 | 4.32 |