Basic Information
ID: ALA3626895
Type: Binding
Description: Inhibition of recombinant human p300 using biotinylated histone H3 (1 to 21 amino acid residues) as substrate preincubated for 10 mins followed by acetyl-CoA addition measured after 10 mins by time resolved fluorescence assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Histone acetyltransferase p300(ALA3784)
Document: ALA3621044
Inhibition of recombinant human p300 using biotinylated histone H3 (1 to 21 amino acid residues) as substrate preincubated for 10 mins followed by acetyl-CoA addition measured after 10 mins by time resolved fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3626895
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 262.72 | 3.10 | 3.10 |
| 246.27 | 2.59 | 2.59 |
| 243.29 | 2.15 | 2.15 |
| 234.31 | 2.51 | 2.51 |
| 360.46 | 2.84 | 2.84 |
| 299.35 | 3.23 | 3.23 |
| 248.33 | 2.82 | 2.82 |
| 365.37 | 4.15 | 4.15 |
| 360.48 | 5.46 | 5.46 |
| 276.75 | 3.16 | 3.16 |
| 311.19 | 3.81 | 3.81 |
| 310.30 | 3.53 | 3.53 |
| 290.37 | 2.82 | 2.82 |