Basic Information
ID: ALA3627446
Type: Binding
Description: Inhibition of Syk in anti-CD32 stimulated CD14+ human monocytes in presence of 90% human blood assessed as phospho-SLP76 level preincubated for 30 mins followed by anti-CD32 stimulation measured after 5 mins by flow cytometric analysis
Format: BAO_0000019
Organism: Homo sapiens
Target: Tyrosine-protein kinase SYK(ALA2599)
Document: ALA3621151
Inhibition of Syk in anti-CD32 stimulated CD14+ human monocytes in presence of 90% human blood assessed as phospho-SLP76 level preincubated for 30 mins followed by anti-CD32 stimulation measured after 5 mins by flow cytometric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3627446
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 321.43 | 3.12 | 3.12 |
| 393.45 | 1.58 | 1.58 |
| 366.43 | 1.88 | 1.88 |
| 381.36 | 2.83 | 2.83 |
| 342.42 | 2.60 | 2.60 |
| 343.41 | 2.00 | 2.00 |
| 342.42 | 2.60 | 2.60 |
| 343.41 | 2.00 | 2.00 |
| 399.47 | 3.28 | 3.28 |
| 344.40 | 2.57 | 2.57 |
| 378.40 | 3.46 | 3.46 |
| 380.38 | 3.43 | 3.43 |
| 380.38 | 3.43 | 3.43 |