Basic Information
ID: ALA3630141
Type: Binding
Description: Inhibition of recombinant human PDE3A assessed as reduction of [3H]-cAMP hydrolysis preincubated for 5 mins followed by [3H]-cAMP addition measured after 20 mins by scintillation proximity assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3630141
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 410.45 | 5.42 | 5.42 |
| 424.48 | 5.75 | 5.75 |
| 452.53 | 6.18 | 6.18 |
| 454.51 | 5.62 | 5.62 |
| 468.53 | 5.76 | 5.76 |
| 498.56 | 5.64 | 5.64 |
| 542.61 | 5.66 | 5.66 |
| 586.66 | 5.67 | 5.67 |
| 453.52 | 5.66 | 5.66 |
| 505.56 | 5.37 | 5.37 |
| 454.51 | 5.62 | 5.62 |
| 410.45 | 5.42 | 5.42 |
| 424.48 | 5.75 | 5.75 |
| 454.51 | 5.62 | 5.62 |
| 454.51 | 5.62 | 5.62 |
| 468.53 | 5.76 | 5.76 |
| 498.56 | 5.64 | 5.64 |
| 542.61 | 5.66 | 5.66 |
| 586.66 | 5.67 | 5.67 |
| 453.52 | 5.66 | 5.66 |
| 505.56 | 5.37 | 5.37 |
| 410.45 | 5.42 | 5.42 |