Assay Report Card

Basic Information

ID: ALA3630308

Type: Functional

Description: Antitumor activity against human SKOV3 cells expressing RFC/PCFT/FRalpha xenografted in folate-deficient diet fed NCR SCID mouse assessed as tumor growth inhibition at 16 mg/kg, iv administered every 4 days on day 3, 7, 11 measured on day 21 relative to control

Organism: Homo sapiens

Cell type: SK-OV-3

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
447.471.121.12