Assay Report Card

Basic Information

ID: ALA3630313

Type: Toxicity

Description: Toxicity in folate-deficient diet fed NCR SCID mouse xenografted with human SKOV3 cells expressing RFC/PCFT/FRalpha assessed as body weight loss at 16 mg/kg, iv administered every 4 days on day 3, 7, 11 relative to control

Organism: Mus musculus

Strain: NCR

Cell type: SK-OV-3

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
447.471.121.12