Basic Information
ID: ALA3630322
Type: Binding
Description: Inhibition of DNA gyrase GyrA/GyrB in Mycobacterium tuberculosis incubated for 30 mins assessed as reduction in supercoiling of relaxed relaxed pBR322 DNA by ethidium bromide staining based agarose gel electrophoresis method
Organism: Mycobacterium tuberculosis
Activity Charts
Bioactivity
Activity Types for Assay ALA3630322
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 401.44 | 2.37 | 2.37 |
| 137.14 | -0.31 | -0.31 |
| 612.63 | 3.63 | 3.63 |
| 822.95 | 4.34 | 4.34 |
| 435.52 | 4.26 | 4.26 |
| 465.55 | 4.26 | 4.26 |
| 453.51 | 4.40 | 4.40 |
| 503.52 | 5.28 | 5.28 |
| 434.54 | 4.29 | 4.29 |
| 464.57 | 4.30 | 4.30 |
| 452.53 | 4.43 | 4.43 |
| 502.54 | 5.31 | 5.31 |
| 462.59 | 4.56 | 4.56 |
| 492.62 | 4.57 | 4.57 |
| 480.58 | 4.70 | 4.70 |
| 530.59 | 5.58 | 5.58 |
| 461.61 | 4.59 | 4.59 |
| 491.64 | 4.60 | 4.60 |
| 479.60 | 4.73 | 4.73 |
| 529.61 | 5.61 | 5.61 |
| 421.50 | 2.68 | 2.68 |
| 451.53 | 2.69 | 2.69 |
| 439.49 | 2.82 | 2.82 |
| 489.50 | 3.70 | 3.70 |
| 420.52 | 2.72 | 2.72 |
| 450.54 | 2.72 | 2.72 |
| 438.51 | 2.86 | 2.86 |
| 488.51 | 3.73 | 3.73 |
| 448.57 | 2.99 | 2.99 |
| 478.60 | 3.00 | 3.00 |
| 466.56 | 3.13 | 3.13 |
| 516.57 | 4.01 | 4.01 |
| 447.59 | 3.02 | 3.02 |
| 477.61 | 3.03 | 3.03 |
| 465.58 | 3.16 | 3.16 |
| 515.58 | 4.04 | 4.04 |
| 407.47 | 3.78 | 3.78 |
| 437.50 | 3.79 | 3.79 |
| 425.46 | 3.92 | 3.92 |
| 475.47 | 4.80 | 4.80 |
| 406.49 | 3.81 | 3.81 |
| 436.51 | 3.82 | 3.82 |
| 424.48 | 3.95 | 3.95 |
| 474.48 | 4.83 | 4.83 |
| 434.54 | 4.08 | 4.08 |
| 464.57 | 4.09 | 4.09 |
| 452.53 | 4.22 | 4.22 |
| 502.54 | 5.10 | 5.10 |
| 433.56 | 4.12 | 4.12 |
| 463.58 | 4.12 | 4.12 |