Basic Information
ID: ALA3630409
Type: Binding
Description: Inhibition of gamma-secretase in HEK293 cells using human APP Swedish/London double mutant as substrate assessed as formation of amyloid beta 42 after 5 to 6 hrs by sandwich immunoassay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3630409
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 370.85 | 5.25 | 5.25 |
| 517.93 | 4.67 | 4.67 |
| 498.98 | 5.25 | 5.25 |
| 454.92 | 4.89 | 4.89 |
| 440.90 | 4.50 | 4.50 |
| 468.91 | 4.41 | 4.41 |
| 517.02 | 4.67 | 4.67 |
| 485.02 | 5.99 | 5.99 |
| 586.00 | 5.02 | 5.02 |
| 518.90 | 5.34 | 5.34 |
| 532.93 | 5.73 | 5.73 |