Basic Information
ID: ALA3631169
Type: Functional
Description: Positive allosteric modulation of human mGlu1 receptor in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliztion by Fluo-4AM dye based fluorescence analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3631169
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 366.76 | 3.99 | 3.99 |
| 382.83 | 4.45 | 4.45 |
| 365.78 | 3.72 | 3.72 |
| 367.75 | 3.38 | 3.38 |
| 367.75 | 3.38 | 3.38 |
| 367.75 | 3.38 | 3.38 |
| 367.75 | 3.38 | 3.38 |
| 383.82 | 3.85 | 3.85 |
| 383.82 | 3.85 | 3.85 |
| 366.76 | 3.12 | 3.12 |
| 366.76 | 3.12 | 3.12 |
| 367.75 | 2.51 | 2.51 |
| 384.80 | 3.24 | 3.24 |
| 370.79 | 3.26 | 3.26 |
| 380.79 | 4.29 | 4.29 |
| 394.81 | 4.55 | 4.55 |
| 422.87 | 5.28 | 5.28 |
| 401.20 | 4.64 | 4.64 |
| 445.66 | 4.75 | 4.75 |
| 434.76 | 5.00 | 5.00 |
| 423.86 | 4.05 | 4.05 |
| 444.85 | 3.39 | 3.39 |
| 442.86 | 5.65 | 5.65 |
| 380.79 | 4.29 | 4.29 |
| 442.86 | 5.65 | 5.65 |
| 394.81 | 4.60 | 4.60 |
| 416.82 | 5.14 | 5.14 |
| 416.82 | 5.14 | 5.14 |
| 394.81 | 4.60 | 4.60 |
| 394.81 | 4.60 | 4.60 |
| 415.23 | 4.95 | 4.95 |
| 415.23 | 4.95 | 4.95 |
| 398.78 | 4.43 | 4.43 |
| 398.78 | 4.43 | 4.43 |
| 381.78 | 3.69 | 3.69 |
| 446.68 | 5.09 | 5.09 |
| 393.83 | 3.30 | 3.30 |