Assay Report Card

Basic Information

ID: ALA3631170

Type: Functional

Description: Positive allosteric modulation of human mGlu1 receptor in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliztion by Fluo-4AM dye based fluorescence analysis relative to glutamate

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
366.763.993.99
383.823.853.85
384.803.243.24
380.794.294.29
394.814.554.55
401.204.644.64
445.664.754.75
434.765.005.00
444.853.393.39
442.865.655.65
380.794.294.29
394.814.604.60
394.814.604.60
415.234.954.95
415.234.954.95
398.784.434.43
398.784.434.43
381.783.693.69