Assay Report Card

Basic Information

ID: ALA3631952

Type: Functional

Description: Positive allosteric modulation of human mGlu1 P1014S mutant receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliztion at 10 uM by Fluo-4AM dye based fluorescence analysis relative to glutamate

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
415.234.954.95
398.784.434.43
381.783.693.69