Assay Report Card

Basic Information

ID: ALA3631964

Type: Functional

Description: Antiviral activity against HCV JFH1 infected in human HuH7-J20 cells assessed as inhibition of viral life cycle by measuring secreted alkaline phosphatase level preincubated with cells for 1 hr followed by viral inoculation for 3 hrs measured at 72 hrs

Organism: Hepacivirus hominis

Strain: genotype 2a JFH-1

Cell type: Huh-7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
244.21-3.01-3.01
171.20-1.26-1.26
408.332.902.90
394.313.223.22
463.204.534.53
528.535.695.69
359.862.572.57
373.892.872.87
292.341.951.95
228.680.380.38