Assay Report Card

Basic Information

ID: ALA3631965

Type: Functional

Description: Antiviral activity against HCV JFH1 infected in human HuH7-J20 cells assessed as inhibition of viral life cycle by measuring secreted alkaline phosphatase level at 10 uM preincubated with cells for 1 hr followed by viral inoculation for 3 hrs measured at 72 hrs relative to control

Organism: Hepacivirus hominis

Strain: genotype 2a JFH-1

Cell type: Huh-7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
177.210.520.52
408.332.902.90
394.313.223.22
463.204.534.53
528.535.695.69
359.862.572.57
373.892.872.87
292.341.951.95
228.680.380.38
191.240.190.19
246.320.230.23
195.200.660.66