Basic Information
ID: ALA3635178
Type: Binding
Description: Inhibition of BACE1 in human SKNBE2 cells expressing wild type human APP695 assessed as reduction in amyloid beta-42 production after 18 hrs by sandwich alphalisa assay
Organism: Homo sapiens
Cell type: SKNBE2
Activity Charts
Bioactivity
Activity Types for Assay ALA3635178
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 362.79 | 2.73 | 2.73 |
| 344.80 | 2.59 | 2.59 |
| 359.36 | 1.48 | 1.48 |
| 377.35 | 1.77 | 1.77 |
| 377.35 | 1.77 | 1.77 |
| 449.77 | 3.35 | 3.35 |
| 449.77 | 3.35 | 3.35 |
| 431.78 | 3.05 | 3.05 |
| 431.78 | 3.05 | 3.05 |
| 403.39 | 2.16 | 2.16 |
| 360.35 | 1.03 | 1.03 |
| 360.35 | 1.03 | 1.03 |
| 380.78 | 3.02 | 3.02 |
| 394.81 | 3.33 | 3.33 |
| 371.35 | 2.24 | 2.24 |