Basic Information
ID: ALA3635222
Type: Binding
Description: Antagonist activity at full length human PXR transfected in human HepG2 cells assessed as reduction in rifaximin-induced receptor transactivation at 50 uM after 18 hrs by luciferase reporter assay
Organism: Homo sapiens
Cell type: HepG2
Activity Charts
Bioactivity
Activity Types for Assay ALA3635222
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 268.36 | 4.83 | 4.83 |
| 440.54 | 5.30 | 5.30 |
| 468.59 | 6.08 | 6.08 |
| 356.46 | 4.16 | 4.16 |
| 472.45 | 3.78 | 3.78 |
| 560.55 | 3.81 | 3.81 |
| 588.61 | 4.59 | 4.59 |
| 616.66 | 5.37 | 5.37 |