Basic Information
ID: ALA3635228
Type: Binding
Description: Antagonist activity against PXR in human HepG2 cells assessed as inhibition of rifaximin-induced CYP3A4 gene expression at 25 uM after 18 hrs by quantitative real-time PCR analysis
Organism: Homo sapiens
Cell type: HepG2
Activity Charts
Bioactivity
Activity Types for Assay ALA3635228
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 268.36 | 4.83 | 4.83 |
| 356.46 | 4.16 | 4.16 |