Basic Information
ID: ALA3635514
Type: Binding
Description: Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 mins by scintillation proximity assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3635514
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 276.34 | 4.01 | 4.01 |
| 294.33 | 4.15 | 4.15 |
| 310.78 | 4.66 | 4.66 |
| 403.49 | 6.13 | 6.13 |
| 421.48 | 6.26 | 6.26 |
| 437.93 | 6.78 | 6.78 |
| 431.54 | 6.61 | 6.61 |
| 424.45 | 6.82 | 6.82 |
| 431.47 | 6.55 | 6.55 |
| 478.52 | 6.86 | 6.86 |
| 450.47 | 6.38 | 6.38 |
| 436.49 | 6.17 | 6.17 |
| 451.46 | 6.59 | 6.59 |
| 421.48 | 6.26 | 6.26 |
| 422.46 | 6.39 | 6.39 |
| 424.45 | 6.82 | 6.82 |
| 404.47 | 5.84 | 5.84 |
| 422.46 | 5.98 | 5.98 |
| 438.91 | 6.49 | 6.49 |
| 422.46 | 5.98 | 5.98 |
| 422.46 | 5.98 | 5.98 |
| 440.45 | 6.11 | 6.11 |
| 418.50 | 6.14 | 6.14 |
| 418.50 | 6.14 | 6.14 |
| 472.47 | 6.85 | 6.85 |
| 434.50 | 5.84 | 5.84 |
| 405.46 | 5.23 | 5.23 |
| 405.46 | 5.23 | 5.23 |
| 403.48 | 6.44 | 6.44 |
| 405.46 | 5.23 | 5.23 |
| 423.45 | 5.37 | 5.37 |
| 388.85 | 5.34 | 5.34 |
| 428.49 | 6.04 | 6.04 |
| 393.45 | 5.16 | 5.16 |
| 411.44 | 5.30 | 5.30 |
| 427.89 | 5.82 | 5.82 |
| 394.43 | 4.56 | 4.56 |
| 425.46 | 5.31 | 5.31 |
| 441.92 | 5.83 | 5.83 |
| 408.46 | 4.57 | 4.57 |
| 436.49 | 6.69 | 6.69 |
| 436.49 | 5.99 | 5.99 |
| 404.47 | 5.84 | 5.84 |
| 422.46 | 5.98 | 5.98 |
| 472.47 | 6.85 | 6.85 |
| 405.46 | 5.23 | 5.23 |