Basic Information
ID: ALA3635532
Type: Binding
Description: Inhibition of recombinant human PDE5A using [3H]cGMP/cGMP as substrate assessed as hydrolysis of [3H]cGMP to [3H]GMP at 1 uM after 30 mins by scintillation proximity assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3635532
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 404.47 | 5.84 | 5.84 |
| 422.46 | 5.98 | 5.98 |
| 438.91 | 6.49 | 6.49 |
| 440.45 | 6.11 | 6.11 |
| 405.46 | 5.23 | 5.23 |
| 393.45 | 5.16 | 5.16 |
| 427.89 | 5.82 | 5.82 |
| 425.46 | 5.31 | 5.31 |
| 441.92 | 5.83 | 5.83 |