Assay Report Card

Basic Information

ID: ALA3635804

Type: ADME

Description: Selectivity ratio of IC50 for wild type EGFR phosphorylation in human A431 cells to IC50 for EGFR L858R/T790M double mutant phosphorylation in human NCI-H1975 cells

Organism: Homo sapiens

Cell type: NCI-H1975

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
511.593.413.41
525.613.723.72
514.593.913.91