Assay Report Card

Basic Information

ID: ALA3635921

Type: Binding

Description: Inhibition of human IDH1 R132H mutant expressed in IPTG-induced Escherichia coli BL21 cells assessed as oxidation of NADPH to NADP+ after 5 mins by spectrophotometry

Organism: Homo sapiens

Cell type: BL21

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
270.242.582.58
456.717.097.09
272.262.512.51
254.242.872.87
286.242.282.28
286.242.282.28
170.120.500.50
286.242.282.28
318.241.691.69
270.242.582.58
456.717.237.23
386.667.397.39
456.717.097.09
256.262.702.70
414.728.028.02
412.707.807.80
456.717.237.23
396.444.794.79
380.445.085.08
576.865.855.85
426.738.468.46
270.283.883.88
426.738.028.02
220.363.393.39
426.738.178.17
1109.31
462.36-0.15-0.15
462.410.060.06
316.445.085.08
428.758.258.25
410.474.984.98
947.17-0.03-0.03
368.394.094.09
408.455.065.06
676.670.070.07
498.44-2.31-2.31
468.46-0.81-0.81
474.737.657.65
338.412.732.73
512.46-2.01-2.01
526.49-1.71-1.71
538.50-1.61-1.61
438.748.798.79
276.291.881.88
358.393.403.40
290.312.182.18
374.392.582.58
194.232.142.14
288.485.115.11
310.484.924.92
452.460.010.01
594.52-1.48-1.48
458.736.116.11
442.737.147.14
442.737.147.14