Basic Information
ID: ALA3636037
Type: Binding
Description: Inhibition of recombinant human topoisomerase 1 assessed as relaxation of supercoiled plasmid DNA pBR322 at 20 uM incubated for 30 mins by agarose gel electrophoresis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3636037
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.08 | 2.08 |
| 250.30 | 3.21 | 3.21 |
| 250.30 | 3.21 | 3.21 |
| 286.33 | 4.05 | 4.05 |
| 266.30 | 2.91 | 2.91 |
| 304.27 | 3.92 | 3.92 |
| 304.27 | 3.92 | 3.92 |
| 320.27 | 3.80 | 3.80 |
| 320.27 | 3.80 | 3.80 |
| 254.26 | 3.04 | 3.04 |
| 254.26 | 3.04 | 3.04 |
| 279.34 | 2.96 | 2.96 |
| 315.38 | 3.81 | 3.81 |
| 343.43 | 4.59 | 4.59 |
| 361.37 | 4.46 | 4.46 |
| 336.44 | 3.50 | 3.50 |
| 377.37 | 4.33 | 4.33 |
| 355.44 | 4.73 | 4.73 |
| 365.43 | 3.60 | 3.60 |
| 357.41 | 3.58 | 3.58 |
| 286.33 | 4.05 | 4.05 |
| 250.30 | 3.21 | 3.21 |
| 250.30 | 3.21 | 3.21 |
| 266.30 | 2.91 | 2.91 |
| 304.27 | 3.92 | 3.92 |
| 320.27 | 3.80 | 3.80 |
| 320.27 | 3.80 | 3.80 |
| 254.26 | 3.04 | 3.04 |
| 254.26 | 3.04 | 3.04 |
| 279.34 | 2.96 | 2.96 |