Basic Information
ID: ALA3636399
Type: Binding
Description: Inhibition of His-tagged KSP motor domain (1 to 369) (unknown origin) assessed as inhibition of microtubule-stimulated KSP ATPase activity preincuabted for 30 mins followed by ATP addition measured after 15 mins by Kinase-Glo assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3636399
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 517.07 | 5.59 | 5.59 |
| 363.48 | 4.12 | 4.12 |
| 393.51 | 4.13 | 4.13 |
| 431.48 | 5.14 | 5.14 |
| 420.49 | 3.88 | 3.88 |
| 389.52 | 4.22 | 4.22 |
| 457.52 | 5.24 | 5.24 |
| 419.55 | 4.23 | 4.23 |
| 403.55 | 4.53 | 4.53 |
| 423.97 | 4.88 | 4.88 |
| 465.62 | 5.89 | 5.89 |
| 481.62 | 6.01 | 6.01 |
| 445.63 | 5.52 | 5.52 |
| 457.52 | 5.24 | 5.24 |
| 423.97 | 4.88 | 4.88 |
| 403.55 | 4.53 | 4.53 |
| 455.50 | 5.63 | 5.63 |
| 417.53 | 4.62 | 4.62 |
| 401.53 | 4.92 | 4.92 |
| 421.95 | 5.26 | 5.26 |
| 463.60 | 6.27 | 6.27 |
| 445.46 | 5.25 | 5.25 |
| 459.49 | 5.03 | 5.03 |
| 461.53 | 5.61 | 5.61 |
| 475.56 | 5.75 | 5.75 |
| 421.59 | 4.77 | 4.77 |