ID: ALA3636516
Type: ADME
Description: Drug metabolism assessed as formation of human MPO-mediated (S)-2-amino-5-((R)-1-(carboxymethylamino)-3-(6-(2,4-dimethoxyphenyl)-1-(2-isopropoxyethyl)-4-oxo-1,4-dihydropyrimidin-2-ylthio)-1-oxopropan-2-ylamino)-5-oxopentanoic acid at 10 uM after 60 mins by LC-MS/MS analysis in presence of H2O2/Cl-/excess GSH
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA3636516
Drug metabolism
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
350.44 | 3.02 | 3.02 |