Assay Report Card

Basic Information

ID: ALA3636889

Type: Binding

Description: Inhibition of TLR4 in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-induced IkappaB-alpha phosphorylation at 10 to 50 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis

Organism: Mus musculus

Strain: BALB/c

Cell type: RAW264.7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
295.30-1.13-1.13