Basic Information
ID: ALA3636899
Type: Binding
Description: Inhibition of B-RAF V600E mutant in human SK-MEL-28 cells assessed as phosphorylation of ERK
Format: BAO_0000219
Organism: Homo sapiens
Cell type: SK-MEL-28
Target: Serine/threonine-protein kinase B-raf(ALA5145)
Document: ALA3632535
Inhibition of B-RAF V600E mutant in human SK-MEL-28 cells assessed as phosphorylation of ERK: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3636899
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 429.52 | 5.16 | 5.16 |
| 518.42 | 6.93 | 6.93 |
| 429.52 | 5.76 | 5.76 |
| 438.54 | 6.19 | 6.19 |
| 514.63 | 7.86 | 7.86 |
| 506.53 | 7.21 | 7.21 |
| 506.53 | 7.21 | 7.21 |
| 524.52 | 7.35 | 7.35 |
| 518.42 | 6.93 | 6.93 |
| 536.41 | 7.07 | 7.07 |
| 482.44 | 6.36 | 6.36 |