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Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate

Basic Information

ID: ALA3636901

Type: ADME

Description: Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate

Format: BAO_0000019

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Target:  Cytochrome P450 3A4(ALA340)

Document:  ALA3632535

Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3636901

IC50

Total(9)

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
518.426.936.93
438.546.196.19
514.637.867.86
506.537.217.21
506.537.217.21
524.527.357.35
518.426.936.93
536.417.077.07
482.446.366.36
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