Basic Information
ID: ALA3636919
Type: Binding
Description: Antagonist activity at human VDR expressed in HEK293 cells co-expressing CMX-GAL4N and TK-MH100x4-LUC assessed as inhibition of 1alpha,25(OH)2VD3-induced transcriptional activity up to 10 uM by beta-galactosidase reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Vitamin D receptor(ALA1977)
Document: ALA3632608
Antagonist activity at human VDR expressed in HEK293 cells co-expressing CMX-GAL4N and TK-MH100x4-LUC assessed as inhibition of 1alpha,25(OH)2VD3-induced transcriptional activity up to 10 uM by beta-galactosidase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3636919
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 544.77 | 6.26 | 6.26 |
| 544.77 | 6.26 | 6.26 |
| 572.83 | 7.04 | 7.04 |
| 572.83 | 7.04 | 7.04 |
| 600.88 | 7.82 | 7.82 |
| 600.88 | 7.82 | 7.82 |
| 588.83 | 6.01 | 6.01 |
| 588.83 | 6.01 | 6.01 |