Basic Information
ID: ALA3637037
Type: Binding
Description: Inhibition of Keap1-NRF2 interaction (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in FITC-9mer NRF2 peptide binding after 1 hr by fluorescence anisotropy assay
Organism: Homo sapiens
Cell type: BL21-DE3
Activity Charts
Bioactivity
Activity Types for Assay ALA3637037
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 507.42 | 5.75 | 5.75 |
| 438.53 | 4.44 | 4.44 |
| 498.58 | 4.46 | 4.46 |
| 614.65 | 3.42 | 3.42 |
| 313.38 | 3.65 | 3.65 |
| 556.62 | 3.94 | 3.94 |
| 498.58 | 4.46 | 4.46 |
| 526.55 | 3.84 | 3.84 |
| 574.52 | 6.48 | 6.48 |
| 574.52 | 6.48 | 6.48 |
| 558.63 | 4.48 | 4.48 |
| 466.58 | 5.06 | 5.06 |
| 524.67 | 4.57 | 4.57 |
| 474.51 | 4.72 | 4.72 |
| 670.76 | 4.37 | 4.37 |
| 578.71 | 5.62 | 5.62 |
| 526.64 | 4.51 | 4.51 |
| 554.69 | 5.29 | 5.29 |
| 612.69 | 2.22 | 2.22 |
| 574.68 | 4.51 | 4.51 |
| 468.56 | 4.45 | 4.45 |
| 536.55 | 5.47 | 5.47 |
| 506.53 | 5.46 | 5.46 |
| 498.58 | 4.46 | 4.46 |
| 584.67 | 4.42 | 4.42 |
| 371.41 | 3.13 | 3.13 |
| 498.58 | 4.46 | 4.46 |
| 498.58 | 4.46 | 4.46 |
| 612.69 | 2.22 | 2.22 |
| 614.65 | 3.42 | 3.42 |
| 555.63 | 3.34 | 3.34 |
| 426.47 | 5.36 | 5.36 |
| 448.52 | 3.31 | 3.31 |